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Grayson Jack Brain Tumor Effectiveness Study

Project Title

A Target Validation Study of Fimepinostat in Children and Young Adults With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG), Recurrent Medulloblastoma, or Recurrent High-Grade Glioma (HGG)

Layman’s summary

Dr. Kline’s trial studies an immunotherapy drug which has never before been used in children and is currently being fast tracked for FDA approval because of its promise for treating cancers. This trial utilizes an oral delivery of medication but assesses treated tumor tissue that is surgically removed to determine concentration of drug and therefore treatment effectiveness. Note: This grant is now led by Sabine Mueller.

Cassie Kline-Nunnally – Transferred to Sabine Mueller

This Project By The Numbers

  • Years Active
    2 years
  • Amount Awarded
  • Institution
    University of California at San Fransisco, Benioff Children’s Hospital