Emmi Grace Applesauce Trial for Kids Who Can’t Swallow Pills
Phase 1 Feasibility Trial of Repeated Convection Enhanced Delivery of HDAC Inhibitor MTX110 (Panobinostat) under real time image guidance for the Treatment of Children with Malignant Midline Gliomas
Dr. Johnson and CKc desired to create a way for patients to benefit from the Indoximod study but were physically unable to swallow pills. Administration via applesauce was first studied but did not prove effective. Dr. Johnson went on to successfully convert the drug into liquid form and deliver the first ever immunotherapy through a patient’s G-tube while providing this potentially life-saving treatment to more children.
This Project By The Numbers
Years Active2 years
InstitutionAugusta University, Georgia Cancer Center