Skip to main content

Santiago Estevez Upfront and Progressive Brain Tumor Immunotherapy Trial

Project Title

Pediatric Phase 2 Studies Using Indoximod with Chemotherapy and Radiation for Children with Advanced Brain Cancer

Layman’s summary

This new, Phase 2 study, tests the hypothesis that treatment with indoximod will enhance the effects of conventional chemotherapy and radiation in children with recurrent brain tumors, or with newly-diagnosed DIPG. It also includes a compassionate-use study that provides indoximod-based therapy to children and young adults with progressive brain cancer who would otherwise not qualify for the Phase 2 trial, including patients who have less common tumors, are unable to swallow whole pills, and who may wish to try using indoximod in combination with additional chemotherapy options.

Theodore Johnson

This Project By The Numbers

  • Years Active
    3 years
  • Amount Awarded
  • Institution
    Augusta University, Georgia Cancer Center